Hormone Therapy Protocols

Hormone Therapy Protocol Kit for Med Spas — TRT, HRT & Pellet Therapy SOPs

This kit gives med spa owners, prescribing clinicians, and clinical directors 10 professionally written hormone therapy SOPs — covering TRT, BHRT, pellet therapy, and DEA-controlled substance compliance. Protect your practice from regulatory risk, document medical necessity, and deliver consistent hormone therapy care with confidence.

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The Case for SOPs

Why Your Hormone Program Needs SOPs

Hormone therapy is one of the most scrutinized services in aesthetics — is your practice protected?

DEA Scrutiny

Testosterone is a DEA Schedule III controlled substance. Without documented controlled substance logs, storage protocols, and disposal records, your practice is exposed to federal enforcement actions — not just state board issues.

Compounding Compliance

BHRT compounding pharmacies require documented prescriber protocols before filling orders. Without written SOPs, your compounding pharmacy relationships — and your ability to access bioidentical hormones — are at risk.

Liability Exposure

Hormone therapy lawsuits are rising. Cardiovascular events, hematocrit elevations, and cancer risk disclosures must be documented. Without proper informed consent and monitoring SOPs, a single adverse event can devastate your practice.

Medical Director Requirements

Hormone therapy programs require documented prescriber oversight for every patient. State medical boards are increasingly requiring written protocols signed by your medical director — verbal agreements are no longer sufficient.

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What's Included in This Kit

Ten complete, implementation-ready SOPs covering every aspect of a modern med spa hormone therapy program — from TRT and BHRT to DEA compliance and patient monitoring.

HT-001

Good Faith Exam for Hormone Patients

Complete compliance documentation protocol for hormone prescribing. Covers medical history collection, physical exam requirements, hormone-specific informed consent, medical necessity documentation, telehealth vs in-person requirements, and prescriber sign-off workflow.

  • Medical history & hormone-specific exam checklist
  • Hormone-specific informed consent requirements
  • Medical necessity documentation for hormone therapy
  • Telehealth vs. in-person exam requirements by state
  • Prescriber review & sign-off workflow
Included in Hormone Therapy Kit
HT-002

Testosterone Replacement Therapy (TRT)

Complete TRT administration protocol covering baseline lab requirements (total T, free T, PSA, CBC, estradiol), injection technique (IM/SQ), dosing initiation and titration, monitoring schedule, side effect management, and hematocrit escalation protocol.

  • Baseline lab panel requirements & reference ranges
  • IM & SQ injection technique with site rotation
  • Dosing initiation & titration schedule
  • Hematocrit escalation protocol (≥52% threshold)
  • Side effect management & monitoring schedule
Included in Hormone Therapy Kit
HT-003

BHRT / Bioidentical Hormone Therapy

Comprehensive bioidentical hormone therapy protocol covering bioidentical hormone evaluation, compounding pharmacy requirements, individualized dosing, patient monitoring, and documentation requirements for compounded prescriptions.

  • Bioidentical hormone candidate evaluation criteria
  • Compounding pharmacy documentation requirements
  • Individualized dosing & formulation selection
  • Off-label use documentation for compounded hormones
  • Patient monitoring & compounded prescription workflow
Included in Hormone Therapy Kit
HT-004

Hormone Pellet Therapy (BioTE)

Comprehensive subcutaneous pellet insertion protocol covering trocar technique, dosing by weight and labs, insertion site care, pellet removal protocol, and the 3–6 month monitoring schedule for optimal outcomes.

  • Subcutaneous pellet insertion & trocar technique
  • Dosing calculator by weight, labs & symptom score
  • Insertion site care & post-procedure instructions
  • Pellet removal protocol & complications management
  • 3–6 month monitoring & re-insertion schedule
Included in Hormone Therapy Kit
HT-005

Thyroid Protocol

Complete thyroid management protocol covering thyroid panel interpretation (TSH, Free T3, Free T4, Reverse T3), T4 vs T3/T4 combination therapy, levothyroxine vs desiccated thyroid selection, monitoring intervals, and dose adjustment protocol.

  • Full thyroid panel interpretation with reference ranges
  • T4 vs T3/T4 combination therapy decision tree
  • Levothyroxine vs. desiccated thyroid selection guide
  • Monitoring intervals & follow-up lab schedule
  • Dose adjustment protocol & escalation criteria
Included in Hormone Therapy Kit
HT-006

DHEA Supplementation Protocol

Complete DHEA supplementation protocol covering baseline DHEA-S testing, dosing by age and sex, topical vs oral administration selection, monitoring for androgenic side effects, and contraindications for specific patient populations.

  • Baseline DHEA-S testing & age-adjusted reference ranges
  • Dosing protocols by age and sex
  • Topical vs. oral administration comparison
  • Androgenic side effect monitoring checklist
  • Contraindications & hormone-sensitive condition screening
Included in Hormone Therapy Kit
HT-007

Hormone Lab Monitoring Protocol

Complete hormone lab management protocol covering full panel requirements, lab frequency by therapy type, reference ranges for all hormone markers, critical value escalation pathways, and documentation requirements for medical director review.

  • Complete hormone panel requirements by therapy type
  • Lab frequency schedule (baseline, 3-month, 6-month)
  • Reference ranges for all hormone markers
  • Critical value escalation & notification protocol
  • Medical director review & documentation workflow
Included in Hormone Therapy Kit
HT-008

Hormone Therapy Informed Consent

Comprehensive informed consent documentation protocol covering risks and benefits documentation, off-label use disclosures for compounded hormones, cardiovascular risk discussion, cancer risk documentation, and patient acknowledgment requirements.

  • Risks & benefits documentation by hormone type
  • Off-label use disclosures for compounded hormones
  • Cardiovascular risk discussion requirements
  • Cancer risk documentation (breast, prostate)
  • Patient acknowledgment & signature requirements
Included in Hormone Therapy Kit
HT-009

DEA Controlled Substance Protocol

Complete DEA compliance protocol covering DEA registration requirements, Schedule III/IV medication handling, controlled substance log requirements, storage requirements, disposal protocol, and DEA audit preparation procedures.

  • DEA registration requirements & renewal checklist
  • Schedule III/IV medication handling procedures
  • Controlled substance log format & requirements
  • Secure storage & disposal protocol
  • DEA audit preparation & documentation checklist
Included in Hormone Therapy Kit
HT-010

Patient Monitoring & Follow-up Protocol

Comprehensive ongoing patient management protocol covering follow-up visit schedules by therapy type, symptom tracking tools, lab review workflows, dose adjustment decision trees, discontinuation criteria, and long-term management documentation.

  • Follow-up visit schedule by therapy type
  • Symptom tracking tools & patient questionnaires
  • Lab review workflow & prescriber sign-off
  • Dose adjustment decision tree (escalate/hold/reduce)
  • Discontinuation criteria & long-term management docs
Included in Hormone Therapy Kit
Complete Hormone Therapy Protocol Kit

Get all 10 protocols in one download — launch your hormone therapy program today

$397 one-time payment

Save $573 vs. buying individually ($97 × 10 = $970). Or get all 62 SOPs for $997 — includes this kit + weight loss, injectables, skin & laser, body & wellness, emergency & operations protocols

Preview Our Quality

See What You're Getting

Don't take our word for it — preview a real SOP from the Hormone Therapy Kit.

📄 Sample Preview: Testosterone Replacement Therapy (TRT) Protocol

SOP-HT-002  |  Version 1.0

Testosterone Replacement Therapy (TRT) Protocol

Schedule III Controlled Substance — DEA Registration & Prescriber Oversight Required

⚠️ DEA SCHEDULE III CONTROLLED SUBSTANCE — Testosterone requires DEA registration, a controlled substance log, secure storage, and physician oversight. Hematocrit must be monitored; dose reductions required at ≥52%.

1 Baseline Lab Requirements

All patients must complete a baseline hormone panel prior to initiating TRT. Labs must be reviewed and approved by the prescribing physician before any testosterone is dispensed or administered.

Required Baseline Labs & Reference Ranges

Lab Test Normal Range Deficiency / Flag Action Required
Total Testosterone 300–1,000 ng/dL <300 ng/dL TRT candidate — document symptoms
Free Testosterone 5–21 pg/mL <5 pg/mL Correlate with total T & symptoms
PSA (Males) <4.0 ng/mL ≥4.0 ng/mL Urology referral before TRT initiation
Hematocrit (HCT) 38.3–48.6% ≥52% Hold dose — escalation protocol
Estradiol (E2) 10–40 pg/mL >40 pg/mL Consider anastrozole — prescriber review
CBC (Complete Blood Count) See reference Abnormal Physician review before initiation

2 Dosing Initiation & Titration

Initial Dosing Protocol — Testosterone Cypionate (IM/SQ)

  • Starting dose: 100–150mg IM weekly or 50–75mg SQ twice weekly
  • Recheck total T, free T, estradiol, and hematocrit at 6–8 weeks
  • Titrate dose up or down based on labs and symptom response

This SOP continues with 8 more sections including: Injection Technique (IM vs SQ), Side Effect Management, Hematocrit Escalation Protocol, Patient Education, Monitoring Schedule, DEA Documentation Requirements, and Quick Reference Card.

Every SOP in the Hormone Therapy Kit follows this same level of depth and detail.

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What You'll Receive

Professional, formatted, ready-to-print SOPs

MedSpa Standards
CONFIDENTIAL

SOP-HT-002  |  Version 1.0  |  Effective: January 2026

Testosterone Replacement Therapy (TRT)

1 Baseline Lab Requirements
Lab
Normal
Flag
Total T
300–1000
<300
HCT
<52%
≥52%
2 Dosing Initiation
MedSpa Standards — DEA Compliant v1.0 | Jan 2026 | Page 1 of 10

Each SOP includes detailed protocols, lab reference tables, checklists, and quick-reference cards — ready to print and implement.

Who This Kit Is For

Hormone therapy is one of the fastest-growing and most regulated services in med spas. These protocols help you launch or scale with confidence.

Med Spas Launching Hormone Therapy Programs

You want to add TRT, BHRT, or pellet therapy to your service menu — but need clinical protocols to train staff, maintain DEA compliance, and stay protected. These SOPs give you the foundation to launch fast and safely.

Already Prescribing Hormones — But No Written Protocols

You're already administering testosterone or BHRT, but you're operating off verbal training or loose guidelines. One DEA inspection or state board inquiry could expose critical gaps. Get compliant before it becomes a problem.

Medical Directors Managing Multiple Providers

You're overseeing hormone prescribing across multiple locations or providers. Without written protocols, inconsistent dosing and monitoring is inevitable. SOPs standardize care across your entire team — reducing risk and improving outcomes.

The Difference

Why Med Spa Owners Choose Us

DEA-Compliant Content

Written specifically for controlled substance handling in hormone therapy programs. Not recycled generic templates.

Ready to Implement

Print them out, train your staff, and you're done. No consultant needed to interpret or customize these protocols.

Expert-Written

Created by healthcare compliance professionals who understand hormone therapy regulations, DEA requirements, and prescribing oversight nationwide.

Fraction of the Cost

Less than 1 hour of healthcare attorney time. A fraction of what a compliance consultant or DEA attorney charges.

What Hormone Clinic Owners Are Saying

R
Dr. Rachel M.
Hormone Clinic Owner, Texas

"We launched our TRT program two years ago with no written protocols — just training from our medical director. When the DEA requested our controlled substance logs during a routine inspection, we had nothing. These SOPs saved us from a nightmare. Implemented everything in one afternoon."

K
Dr. Kevin S.
Medical Director, Florida

"I was overseeing TRT and BHRT across three locations with zero standardization. Different providers were monitoring hematocrit at different intervals. The lab monitoring protocol alone was worth the price — now everyone follows the same schedule and I sleep better at night."

J
Jessica T., NP
Hormone Therapy NP, Colorado

"We added pellet therapy without a written insertion protocol — just hands-on training from a BioTE rep. When our compounding pharmacy asked for documentation, we had nothing. These SOPs gave us everything we needed to satisfy the pharmacy and protect ourselves clinically."

A
Amanda L.
Med Spa Owner, Arizona

"The informed consent SOP alone is worth the price. We had patients signing generic consent forms with no cancer risk or cardiovascular risk documentation. After a patient lawsuit scare, we knew we needed proper documentation. These protocols completely overhauled our consent process."

The Reality

Without SOPs vs. With SOPs

The difference between reactive chaos and proactive compliance

Without Written Protocols

  • No DEA controlled substance log — federal violation exposure
  • Inconsistent hematocrit monitoring — patient safety risk
  • Verbal-only dosing — no documented medical necessity
  • No cancer/cardiovascular risk disclosures in consent
  • Compounding pharmacy unable to verify prescriber protocol
  • Medical director exposed to liability without signed oversight docs

With These SOPs

  • Documented DEA compliance — audit-ready at any time
  • Standardized lab schedule — every patient monitored consistently
  • Clear dose adjustment protocol with prescriber sign-off workflow
  • Complete informed consent with all required risk disclosures
  • Compounding pharmacy documentation requirements satisfied
  • Medical director protected with documented oversight protocols

100% Satisfaction Guarantee

If these protocols don't save you time, reduce compliance risk, or improve your hormone program operations within 30 days, we'll refund every penny. No questions asked.

We've never had a single refund request. These SOPs work.

DEA doesn't give warnings

The DEA Doesn't Give Second Chances — Document Your Hormone Program Now

Most hormone clinics don't create written protocols until after a DEA audit, a patient lawsuit, or a state board inquiry. By then, the damage is done. One inspection with no controlled substance log can result in DEA registration revocation — ending your ability to prescribe testosterone entirely.

Get ahead of the problem. Implement these SOPs today.

Compare Options

How We Compare

Feature MedSpa Standards No Protocol Build It Yourself
Price $397 one-time Free (DEA risk) $3,000+ consultant fee
Implementation Ready Same day N/A Months of research
DEA Controlled Substance Compliant ❌ Federal exposure ❌ Uncertain
Professionally Written ❌ No documentation ❌ No guarantee
Staff Training Tool ❌ Verbal only ❌ Inconsistent
DEA Audit Ready ❌ Major federal risk ❌ Unlikely
Money-Back Guarantee 30 days
Simple Pricing

Get Your Hormone Therapy Protocols

Choose the right protocol package for your practice — from a single SOP to our complete hormone therapy bundle.

Individual SOP

Perfect for filling a specific gap

$97 / per SOP
  • 1 SOP of your choice
  • Professional DOC format
  • Instant download
  • Step-by-step clinical guidance
Browse Individual Protocols
Best Value

Hormone Therapy Protocol Kit

Complete hormone program coverage

Save $573 vs. buying individually ($97 × 10 = $970)
$970 if bought separately
$397 / one-time

🎉 Complete 10-SOP kit — everything you need in one download

  • All 10 hormone therapy protocols
  • DEA controlled substance documentation
  • Professional DOC format
  • Instant download
  • Free updates for 1 year
  • 30-day money-back guarantee
Instant PDF download — implement today
Nationally compliant — works in all 50 states
Written by med spa compliance specialists
Used by hundreds of med spa practices nationwide
30-Day Money-Back Guarantee

Complete Practice Suite

Everything — all 62 SOPs in one bundle

$997 / one-time
  • 10 weight loss protocols
  • 10 injectables protocols (Botox, Filler, etc.)
  • 9 skin & laser protocols
  • 10 body & wellness protocols
  • 10 hormone therapy protocols
  • 8 emergency protocols
  • 5 operations & compliance SOPs
  • Lifetime updates
Get All 62 SOPs — $997
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Related Reading

Frequently Asked Questions

Common questions from med spa owners about hormone therapy protocols

Are these protocols compliant in all 50 states?

Yes. These are nationally compliant baseline protocols written to meet FDA, DEA, and industry standards applicable in all U.S. states. Your medical director or prescribing clinician must review them for any state-specific controlled substance or supervision requirements. The clinical and compliance protocols themselves are nationally applicable and ready for immediate implementation.

What format do I receive the SOPs in?

All SOPs are delivered as professionally formatted PDF documents. You'll receive instant download links via email immediately after purchase. You can print them, store them digitally, or upload them to your practice management software — and customize them with your practice name and medical director information.

Can I customize these protocols for my practice?

Absolutely. These are provided as editable templates. You can customize them with your practice name, medical director and prescriber information, compounding pharmacy details, and any state-specific requirements. Most practices use the kit as-is and simply add their medical director's signature to the approval pages.

Do I need a medical director to offer hormone therapy?

Yes. Testosterone is a DEA Schedule III controlled substance that requires a licensed physician or DEA-registered prescriber. Your practice must have physician oversight for TRT, BHRT, and pellet therapy. These protocols include DEA compliance documentation and a medical director approval page required for implementation in any med spa setting.

How quickly can I implement these after purchase?

Most practices implement same-day or within 48 hours. You receive instant access via download link after purchase. Print the SOPs, review them with your prescribing clinician, and have your medical director sign the standing orders and DEA compliance checklist. No consultant or additional formatting required.

Do these protocols include the lab monitoring schedule for TRT?

Yes. The TRT protocol requires baseline labs before initiation, a follow-up panel at 6–8 weeks, then monitoring every 3–6 months once stable. The Hormone Lab Monitoring Protocol provides a complete schedule by therapy type including testosterone levels, hematocrit, PSA, and metabolic panel timing.

Is this a one-time payment or subscription?

One-time payment. $397 gets you lifetime access to all 10 hormone therapy protocols. No recurring fees, no subscriptions, no hidden costs. If we release updated versions in the first year, you'll receive them at no charge. Need all 62 SOPs? Check out the Complete Practice Suite for $997.

Free Guides

Free Resources for Hormone Clinic Owners

Deep dives into hormone therapy compliance, TRT documentation, and DEA best practices.

Protect Your Hormone Program. Stay DEA Compliant.

Get all 10 professionally written hormone therapy protocols instantly. Stop operating without documentation — implement compliance today.

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